The SMC loader Scc2 promotes ncRNA biogenesis and
Apr 24, 2015 · The SMC loader Scc2 promotes ncRNA biogenesis and translational fidelity in Saccharomyces cerevisiae par Musinu Zakari. Thèse de doctorat en Biologie Cellulaire et Moléculaire. Sous la direction de Jennifer L. Gerton. Soutenue le Liming15.
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The SMC loader Scc2 promotes ncRNA biogenesis and
Apr 24, 2015 · The SMC loader Scc2 promotes ncRNA biogenesis and translational fidelity in Saccharomyces cerevisiae par Musinu Zakari. Thèse de doctorat en Biologie Cellulaire et Moléculaire. Sous la direction de Jennifer L. Gerton. Soutenue le Kefid15.
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Cohesion promotes nucleolar structure and function
Dec 04, 2013 · The SMC Loader Scc2 Promotes ncRNA Biogenesis and Translational Fidelity 15 July 2015 | PLOS Genetics, Vol. 11, No. 7 A Sequence-Specific Interaction between the Saccharomyces cerevisiae rRNA Gene Repeats and a Locus Encoding an RNA Polymerase I …
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Publications | Gerton Lab
The SMC Loader Scc2 Promotes ncRNA Biogenesis and Translational Fidelity. Zakari M, Trimble Ross R, Peak A, Blanchette M, Seidel C, Gerton JL. PLoS Genet. The SMC loader Scc2 regulates gene expression. Zakari M, Gerton JL. Cell Cycle. 2015;14:943. 2014.
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PLOS Genetics: Publishing science, accelerating research
Jul 01, 2015 · MoSET1 (Histone H3K4 Methyltransferase in Magnaporthe oryzae) Regulates Global Gene Expression during Infection-Related Morphogenesis . Kieu Thi Minh Pham, Yoshihiro Inoue, Ba Van Vu, Hanh Hieu Nguyen, Toru Nakayashiki, Ken-ichi Ikeda, Hitoshi Nakayashiki
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Mutation Spectrum and Genotype–Phenotype Correlation in
Avi Matityahu, Itay Onn, A new twist in the coil: functions of the coiled-coil domain of structural maintenance of chromosome (SMC) proteins, Current Genetics, 10.1007/s00294-017-0735-2, …
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Jennifer L. Gerton - Publications
The SMC Loader Scc2 Promotes ncRNA Biogenesis and Translational Fidelity. Plos Genetics. 11: e1005308. The SMC loader Scc2 regulates gene expression. Cell Cycle (Georgetown, Tex.). 14: 943. PMID 25715109 DOI: 10.1080/15384101.2015.1010959 : 0.88: 2015: Xu B, Sowa N, Cardenas ME, Gerton JL. L-leucine partially rescues translational and
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Mechanisms of cohesin-mediated gene regulation and lessons
Mar 01, 2014 · 1.1. Structural features of cohesin. Cohesin consists of the SMC family proteins SMC1 (also known as SMC1A) and SMC3 as a heterodimer with the two non-SMC components Rad21 (also called Mcd1 or Scc1) and Scc3 (also called SA or STAG) .SMC1 and SMC3 interact through their central hinge regions, while their respective paired amino- and carboxyl-terminal globular domains are further …
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The SMC Loader Scc2 Promotes ncRNA Biogenesis and
The SMC Loader Scc2 Promotes ncRNA Biogenesis and Translational Fidelity. The Scc2-Scc4 complex is essential for loading the cohesin complex onto DNA. Cohesin has important roles in chromosome segregation, DSB repair, and chromosome condensation. Here we report that Scc2 is important for gene expression in budding yeast.
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(PDF) The SMC Loader Scc2 Promotes ncRNA …
Scc2 is also important for the production of the RNA components of ribosomes. Our findings suggest Scc2 normally promotes the production of RNAs that support translational fidelity.
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IJMS | Free Full-Text | Role of the DDX11 DNA Helicase in
Warsaw breakage syndrome (WABS) is a genetic disorder characterized by sister chromatid cohesion defects, growth retardation, microcephaly, hearing loss and other variable clinical manifestations. WABS is due to biallelic mutations of the gene coding for the super-family 2 DNA helicase DDX11/ChlR1, orthologous to the yeast chromosome loss protein 1 (Chl1). WABS is classified in the group of
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Tesis: "NcRNA 886" – Grafiati
Consulte los 50 mejores tesis para su investigación sobre el tema "NcRNA 886". Junto a cada fuente en la lista de referencias hay un botón "Agregar a la bibliografía". Pulsa este botón, y generaremos automáticamente la referencia bibliográfica para la obra elegida en el estilo de cita que necesites: APA, MLA, Harvard, Vancouver, Chicago, etc.
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Publications | Gerton Lab
The SMC Loader Scc2 Promotes ncRNA Biogenesis and Translational Fidelity. Zakari M, Trimble Ross R, Peak A, Blanchette M, Seidel C, Gerton JL. PLoS Genet. The SMC loader Scc2 regulates gene expression. Zakari M, Gerton JL. Cell Cycle. 2015;14:943. 2014.
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Transport of DNA within cohesin involves clamping on top
Sep 15, 2020 · Scc2 promotes entrapment of DNA in E-S/E-K compartments by promoting its binding to engaged SMC ATPase heads, while Scc3 promotes entrapment inside S-K rings. These findings are supported by our cryo-EM structure that reveals the molecular basis of the clamped E-S/E-K state and also by recent cryo-EM structures containing cohesin, DNA, and Scc2
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Promotion of Hyperthermic-Induced rDNA Hypercondensation
Mar 01, 2020 · Ribosome biogenesis is tightly regulated through stress-sensing pathways that impact genome stability, aging and senescence. In Saccharomyces cerevisiae, ribosomal RNAs are transcribed from rDNA located on the right arm of chromosome XII. Numerous studies reveal that rDNA decondenses into a puff-like structure during interphase, and condenses into a tight loop-like structure during mitosis.
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Allelic Spectra of Risk SNPs Are Different for Environment
Allelic Spectra of Risk SNPs Are Different for Environment/Lifestyle Dependent versus Independent Diseases
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E3 ubiquitin ligase Bre1 couples sister chromatid cohesion
Oct 23, 2017 · Most of the DNA in a cell is stored in structures called chromosomes. During every cell cycle, each cell needs to replicate its chromosomes, hold the two chromosome copies (also known as "sister chromatids") together before cell division, and distribute them equally to the two new cells. Each step must be executed accurately otherwise the new cells will have extra or missing chromosomes
Get a quoteThree options to stretch out with long-reach excavators
Sep 17, 2020 · Attached in the place of the excavator stick, these attachments are designed to improve productivity on challenging excavation projects. The arm is designed using a combination of rope and hydraulic cylinders, allowing it to telescope out and then retract with a full load smoothly and quickly, according to Cosben.
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IJMS | Free Full-Text | PDS5A and PDS5B in Cohesin
Precocious dissociation of sisters 5 (PDS5) is an associate protein of cohesin that is conserved from yeast to humans. It acts as a regulator of the cohesin complex and plays important roles in various cellular processes, such as sister chromatid cohesion, DNA damage repair, gene transcription, and DNA replication. Vertebrates have two paralogs of PDS5, PDS5A and PDS5B, which have redundant
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The SMC Loader Scc2 Promotes ncRNA Biogenesis and
Jul 15, 2015 · For instance, a recent report suggested Scc2 may help maintain a nucleosome-free region, which could potentially promote both SMC complex loading and gene expression. Since Scc2 target genes contribute to translation, a decrease in their expression may negatively affect translation.
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